How important is the role of stellar feedback in the regulation of star formation in galaxies? Revisiting high-resolution HI 21cm VLA data from the LITTLE THINGS survey, we investigated the relationship between interstellar gas kinematics and massive star formation in one of the smallest nearby galaxies, dwarf irregular DDO 43 (SFR of 17.72 ± 0.03 × 10−4 M⊙/yr, at a distance of 7.8 Mpc). The line profiles of HI 21cm spectra were carefully analysed, and the distribution of derived spectral line properties was compared to available GALEX far-ultraviolet and WISE infrared data. We will report and interpret the weak correlation found and briefly discuss the global and local gas flows traced in DDO 43.