Tim Holy
Timothy E. Holy is the Alan A. and Edith L. Wolff Professor of Neuroscience and Biomedical Engineering at Washington University in St. Louis. His lab combines technological innovation with analysis of the rules governing neuronal function and computation. His work on Julia includes contributions to the type system, the array and broadcasting infrastructure, the standard library, and developer tools like the profiler, debugger, Revise, and many others.
Session
Biology is driven by interactions: between transcription factors and genes, receptors and ligands, and pre- and post-synaptic neurons. To gain insights about complex systems, embedding methods are commonly used to represent pairwise similarity relationships; however, we lack tools for coembedding two or more classes of interacting objects. I will present new machine learning tools for coembedding interacting systems. A distinguishing feature is the representation of entities by Gaussian probability distributions rather than points, which results in a quadratic compression of dimensionality, enabling quantiatively-accurate visualization of more complex systems than is possible by traditional techniques.