I am a doctoral candidate in Vanderbilt’s human genetics PhD training program.
Determining one’s risk of developing various diseases throughout one’s lifetime is important for pursuing good health. An emerging method for performing this calculation is the Polygenic Risk Score, or PRS. A PRS method allows one to construct a model of risk of acquiring a certain disease given one’s own genome and provides a simple numerical result representing that risk. We will describe how we ported a widely used PRS program to Julia and the performance and usability that we gained.