I am a postdoctoral researcher at Ghent University. My interest is in using computational intelligence to understand and design biological systems.
The alignment of two or more biological sequences is one of the main workhorses in bioinformatics because it can quantify similarity and reveal conserved patterns. We provided a differential version of the two most popular algorithms for sequence alignment: the Needleman–Wunsch and Smith-Waterman algorithms. Using ChainRulesCore.jl, the gradients can be used directly in combination with bioinformatics and machine learning libraries.