Systems (e.g., Hadoop, Mysql, Hive) contain a vast number of configuration parameters that control the performance of the system. However, it is a challenging task to tune the parameters, as there are more than hundreds of parameters and the best parameters are different for different workloads. To solve this problems, we design an AI-based automatic parameter tuning system (named A-Tune). The experimental results show that the performance of mysql improves 30%-40%.