Crime has been continuously changing and diversifying. It has traditionally to be dealt with up-to-date legislation based on scientific and technological revolutions. This includes a national DNA database to protect public safety where cases are complicated or unable to find perpetrators. DNA databanks have been set up in most developed countries, namely the United States, the United Kingdom, the European Union, and the People's Republic of China. In Southeast Asian countries, there are national genetic databases in Singapore and Malaysia. However, there is no DNA center in Thailand to keep samples or profiles from convicted criminal offenders and biological material from crime scenes due to the conflicts between individual rights and public safety. Moreover, genetic and juridical or legal literacy of a forensic DNA database has not been firmly established in the public's acceptance. The Central Institute of Forensic Science (CIFS) is proposing the draft legal in DNA Databank Law that leads the way to establish the legal basis for creating a National DNA Database. Since the scope of the collected DNA and personal data are not only confined to suspects or convicted criminals, constitutional rights might have to be revised. This issue could provide lawmakers and enforcers an opportunity to explore and better understand the psychosocial elements that underpin public support for the DNA database that is only to be confined to suspects or convicted criminals.